The decision to administer an anticoagulant is based on the assessment that the risk of thrombosis and its complications is a greater clinical concern than the risk of bleeding and its complications for the specific patient at a specific … addresses anticoagulant therapy: Reduce the likelihood of patient harm associated with the use of anticoagulant therapy. Aim Anticoagulant therapy is considered a high-risk medication strategy with a narrow therapeutic window and the need for close monitoring, particularly with vitamin K antagonists. In 2008, The Joint Commission published a new National Patient Safety Goal (NPSG) to address high-risk anticoagulation … Anticoagulant therapy has appeared and disappeared in the different guidelines and important documents detailing the treatment of DIC. population had anticoagulation held for less than 5 days. A high percent- For the prevention of stroke, anticoagulant therapy was established as the therapy of choice for the treatment of patients with AF (8-10). Common Risks Associated with Anticoagulants (heparin, low-molecular weight heparin, warfarin) Duplicate or concurrent therapy. these high-risk patients. Reduce the likelihood of patient harm associated with the use of anticoagulation Therapy Why? Anticoagulation therapy is recommended for preventing, treating, and reducing the recurrence of venous thromboembolism, and preventing stroke in … There is no anticoagulant that reduces thrombotic risk without simultaneously increasing the risk of bleeding to some degree. Anticoagulation to reduce this risk is of concern because of the possibility of excessive bleeding or postoperative hematomas and associated neurologic deficits. Anticoagulation therapy using vitamin K inhibitors reduces the rate of stroke by 30% in high-risk patients, indicated by CHADS2 or CHA2DS2VASc risk scores ≥2 (11-12). Anticoagulation medications are high-risk drugs.1 There is a very small window for therapeutic dosing: too much of a drug can cause bleeding, and too little may lead to clotting. There seems to be a paucity of literature on this topic. Element of performance (EP) 4 addresses DOACs: The organization has a written policy addressing the need for baseline and ongoing laboratory tests to monitor and adjust anticoagulant therapy. Therapy Indication for Anticoagulant Therapy Venous Thromboembolism Atrial Fibrillation Mechanical Heart Valve Low Ejection Fraction with Normal Sinus Rhythm from Peri-operative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th Edition. Identification of common, preventable, and measurable healthcare-associated anticoagulant ADEs is a key component of quality improvement Methods. Summary of Background Data. Thromboembolic complications after major spinal surgery is a significant risk for patients. Anticoagulation is a high risk treatment, which commonly leads to adverse drug events due to the complexity of dosing these medications, monitoring their effects, and ensuring patient compliance with outpatient therapy. INTRODUCTION. Approved anticoagulants for clinical use in the acute setting of acute coronary syndrome (ACS)/percutaneous coronary interventions (PCI) patients are classified according to their mechanism of action. Note: For all patients receiving General The role of anticoagulant therapies is to block the activity of coagulation factors. Anticoagulant medications, which include warfarin, heparin, low-molecular weight heparin, and direct oral anticoagulants, are one of four medication classes commonly identified as a cause of ADEs. Anticoagulant agents may block specific targets in the coagulation cascade. None of the 7 patients who experienced a thromboem-bolic event received bridging therapy (ie, short-acting anti-coagulation medication use), despite the fact that 2 of these patients were technically high risk because of active malignancy and recent DVT, respectively. Unrecognized concomitant use of anticoagulants, particularly unfractionated heparin prescribed upon admission and low-molecular weight heparin prescribed initially in the emergency department or other outpatient area and continued upon admission. American College of Chest Physicians Evidence Based